Top Medical Practice Management Software Comparison
By Amanda Reyes | Published: 2025-04-09 | Category: Medical Practice Management Software
About Medical Practice Management Software
Software designed to streamline administrative and clinical operations within medical practices, managing tasks like scheduling, billing, and patient communication. These platforms help optimize workflows, improve financial performance, and enhance patient care coordination.
Scoring Criteria
- → Scheduling
- → Billing & Coding
- → Patient Engagement
- → Reporting & Analytics
- → Integrations
- → Usability
- → Support
- → Pricing Value
The Best Medical Practice Management Software

Greenway Intergy Practice Management
By Greenway Health
A comprehensive practice management system often integrated with Greenway's Intergy EHR, catering to ambulatory practices.
Platforms & Use Cases
Platforms: Cloud-based, On-Premise Option
Best For: Mid-sized Practices, Multi-specialty Groups, Ambulatory Care
Key Features
- ✓Advanced Scheduling: Rule-based scheduling across multiple locations and providers.
- ✓Revenue Cycle Management Tools: Features for claims management, denial tracking, and payment processing.
- ✓Reporting and Analytics: Tools for monitoring financial health and operational efficiency.
- ✓Patient Communication Tools: Integrated messaging and appointment reminders.
Scorecard (Overall: 6.9 / 10.0)
Pricing
Quote-Based
Contact Vendor
- Customized based on practice needs and modules
Limitations: Pricing not publicly available
Pros
- + Comprehensive feature set for ambulatory practices
- + Strong integration with Intergy EHR
- + Good scheduling capabilities
Cons
- - Interface can appear dated
- - Support quality reported as variable
- - Can be complex to navigate
- - Pricing transparency is low
Verdict
"A capable PM solution for practices already invested in or considering the Greenway ecosystem, particularly mid-sized ambulatory groups."

RXNT Practice Management
By RXNT
A cloud-based, integrated solution offering EHR, e-prescribing, and practice management with straightforward pricing.
Platforms & Use Cases
Platforms: Cloud-based, Mobile App (iOS/Android)
Best For: Small to Mid-sized Practices, Practices needing affordable integrated solutions
Key Features
- ✓Centralized Scheduling: Manage appointments, check eligibility, and send automated reminders.
- ✓Medical Billing: Includes claim scrubbing, electronic submission, ERA posting, and reporting.
- ✓Patient Portal: Offers online scheduling, bill pay, and secure messaging.
- ✓Mobile Charge Capture: Allows providers to capture charges on the go via mobile app.
Scorecard (Overall: 7.1 / 10.0)
Pricing
Practice Management
$110.00 / Per Provider/Month
- Scheduling
- Billing
- Reporting
Limitations: EHR and eRx separate
Full Suite (EHR+PM+eRx)
$175.00 / Per Provider/Month
- Full integrated suite
- Patient Portal
- Mobile Apps
Limitations: Fewer features than some higher-priced options
Pros
- + Very competitive and transparent pricing
- + Easy-to-use interface
- + Good mobile functionality
- + Solid core features for small practices
Cons
- - Reporting and analytics are basic
- - Fewer integrations compared to larger vendors
- - Lacks deep features for complex specialties or large groups
Verdict
"An excellent value proposition for small to mid-sized practices needing a straightforward, affordable, and integrated PM/EHR solution."

CureMD Practice Management
By CureMD
An all-in-one, cloud-based solution combining EHR, practice management, and billing services with a focus on specialty workflows.
Platforms & Use Cases
Platforms: Cloud-based, Mobile App (iOS/Android)
Best For: Small to Mid-sized Practices, Specialty Clinics, Urgent Care
Key Features
- ✓Specialty-Focused Workflows: Tailored templates and workflows for various medical specialties.
- ✓Smart Encounter Forms: Streamlines charge capture directly from clinical documentation.
- ✓Integrated Clearinghouse: Built-in claims processing and management tools.
- ✓Patient Portal: Secure access for patients to manage appointments, view summaries, and communicate.
Scorecard (Overall: 7.4 / 10.0)
Pricing
Practice Management
$195.00 / Per Provider/Month (Estimate)
- Scheduling
- Billing
- Reporting
Limitations: EHR separate
All-in-One (EHR+PM)
$295.00 / Per Provider/Month (Estimate)
- Full Suite
- eRx
- Labs
- Patient Portal
Limitations: RCM services typically extra or percentage-based
Pros
- + Strong specialty support
- + All-in-one platform simplifies integration
- + Competitive pricing
- + Good core PM functionality
Cons
- - Interface can feel less modern than some competitors
- - Customization might be limited compared to enterprise systems
- - Some reports could be more advanced
Verdict
"A solid, cost-effective all-in-one solution, particularly well-suited for specialty practices looking for tailored workflows."

DrChrono Practice Management
By EverHealth (formerly DrChrono)
An iPad and cloud-based EHR and practice management platform known for its mobile-first approach and customization options.
Platforms & Use Cases
Platforms: Cloud-based, Mobile App (iOS)
Best For: Small Practices, Mobile Practices, Specialty Clinics (esp. those using iPads)
Key Features
- ✓Mobile Scheduling: Manage appointments easily from an iPad or web browser.
- ✓Integrated Billing: Streamlined charge capture from EHR notes, claim submission, and ERA posting.
- ✓Customizable Medical Forms: Build custom forms for patient intake and charting.
- ✓Patient Portal (OnPatient): Portal for appointments, secure messaging, form completion, and payments.
Scorecard (Overall: 7.0 / 10.0)
Pricing
Prometheus
$500.00 / Per Provider/Month (Estimate)
- EHR
- PM
- eRx
- Basic Billing
Limitations: RCM services extra
Hippocrates
$600.00 / Per Provider/Month (Estimate)
- All Prometheus features
- Advanced Billing features
- API access
Limitations: RCM services extra
ApolloPlus (RCM)
Contact Vendor
- Full EHR/PM suite
- Dedicated RCM service
Limitations: Pricing tied to collections
Pros
- + Excellent mobile experience (iOS focus)
- + Highly customizable forms and templates
- + Good integration between EHR and PM
- + Modern API for integrations
Cons
- - Primarily focused on Apple ecosystem
- - Reporting features less robust than some competitors
- - Pricing can be high for smaller practices not using RCM service
Verdict
"Best suited for practices that heavily utilize iPads and value a mobile-first workflow with strong customization capabilities."

CareCloud Central
By CareCloud
A modern, cloud-based practice management system focused on user experience and workflow automation, often paired with CareCloud Charts EHR.
Platforms & Use Cases
Platforms: Cloud-based, Mobile App (iOS)
Best For: Small to Mid-sized Practices, Specialty Groups, High-performance Practices
Key Features
- ✓CollectiveIQ Billing Rules Engine: Proactive claim scrubbing and denial prevention based on aggregated data.
- ✓Advanced Scheduling: Intuitive drag-and-drop scheduler with multi-resource views and automated waitlists.
- ✓Patient Experience Management (Breeze): Modern patient portal and check-in tools for streamlined interactions.
- ✓Analytics Suite: Real-time dashboards and customizable reports for financial and operational tracking.
Scorecard (Overall: 7.9 / 10.0)
Pricing
Central (PM)
$349.00 / Per Provider/Month (Estimate)
- Scheduling
- Billing
- Analytics
- Basic Patient Tools
Limitations: EHR and advanced patient engagement separate
Concierge (RCM Service)
Contact Vendor
- Full PM Suite
- Dedicated RCM team
- Advanced Analytics
Limitations: Based on % of collections
Pros
- + Modern, user-friendly interface
- + Strong focus on workflow automation
- + Excellent patient engagement tools (Breeze)
- + Effective billing rules engine
Cons
- - Can be more expensive than some options
- - Mobile app primarily iOS
- - Some reports require higher tiers
Verdict
"A great option for practices prioritizing a modern user experience, efficient workflows, and strong patient engagement capabilities."

eClinicalWorks Practice Management
By eClinicalWorks
A widely used, unified EHR and practice management solution offering a broad range of features for various practice sizes.
Platforms & Use Cases
Platforms: Cloud-based, Desktop Application, Mobile App (iOS/Android)
Best For: Small to Large Practices, Community Health Centers, Specialty Clinics
Key Features
- ✓Integrated Scheduling: Appointment management linked directly with EHR and billing.
- ✓Billing and RCM: Tools for charge entry, claims submission, ERA posting, and collections.
- ✓Patient Portal (Healow): Patient engagement platform for appointments, communication, payments, and health records.
- ✓Reporting Dashboards: Visual dashboards for key performance indicators.
Scorecard (Overall: 7.4 / 10.0)
Pricing
EHR with PM
$449.00 / Per Provider/Month (Estimate)
- Integrated EHR/PM
- Patient Portal
- Basic RCM Tools
Limitations: Some advanced features/services may cost extra
PM Only
$299.00 / Per Provider/Month (Estimate)
- Scheduling
- Billing
- Reporting
Limitations: Requires integration if using separate EHR
Pros
- + Comprehensive, unified platform
- + Strong patient engagement tools (Healow)
- + Widely adopted, large user base
- + Relatively affordable for the feature set
Cons
- - User interface often cited as cluttered or dated
- - Customer support experiences can be inconsistent
- - Can feel less intuitive than some competitors
Verdict
"A feature-rich, unified solution popular among practices seeking comprehensive capabilities, especially strong patient engagement, at a competitive price point, despite usability concerns."

NextGen Enterprise PM
By NextGen Healthcare
An enterprise-level practice management system designed for larger practices and health systems, often paired with NextGen Enterprise EHR.
Platforms & Use Cases
Platforms: Cloud-based, On-Premise Option
Best For: Mid-sized to Large Practices, Multi-specialty Groups, ACOs, Health Systems
Key Features
- ✓Enterprise Scheduling: Handles complex scheduling needs across multiple providers, locations, and resources.
- ✓Revenue Cycle Management: Comprehensive tools for claims management, denial prevention, and payment posting.
- ✓Contract Management: Tools to manage complex payer contracts and reimbursement rules.
- ✓Analytics & Reporting: Sophisticated reporting for financial performance, operational efficiency, and quality measures.
Scorecard (Overall: 7.8 / 10.0)
Pricing
Quote-Based
Contact Vendor
- Customized based on practice size and required modules
Limitations: Pricing not publicly available, generally higher cost
Pros
- + Highly scalable for large organizations
- + Deep feature set for complex operations
- + Strong integration capabilities
- + Robust reporting and analytics
Cons
- - Complex implementation
- - Higher cost compared to small practice solutions
- - User interface can be dated
- - Steeper learning curve
Verdict
"Ideal for large, complex organizations needing extensive customization, robust reporting, and scalability, but overkill for smaller practices."

AdvancedMD
By AdvancedMD
A comprehensive cloud suite offering modular EHR, practice management, billing, and patient engagement tools for various practice sizes.
Platforms & Use Cases
Platforms: Cloud-based, Mobile App (iOS/Android)
Best For: Small to Large Practices, Specialty Clinics, Mental Health, Physical Therapy, Billing Services
Key Features
- ✓Flexible Scheduling: Advanced scheduling with custom rules, templates, and multi-location support.
- ✓Claim Center: Centralized dashboard for managing the entire claims lifecycle, including scrubbing and tracking.
- ✓Reporting Suite: Extensive library of standard and customizable reports for financial and operational insights.
- ✓Patient Engagement Tools: Includes portal, automated reminders, reputation management, and telehealth options.
Scorecard (Overall: 8.0 / 10.0)
Pricing
Practice Management
$180.00 / Per Provider/Month (Estimate)
- Scheduling
- Billing
- Basic Reporting
Limitations: EHR and advanced features extra
Bundle (PM + EHR)
$450.00 / Per Provider/Month (Estimate)
- Full PM & EHR
- Patient Portal
- ePrescribing
Limitations: Can become expensive with add-ons
Pros
- + Highly customizable
- + Robust reporting capabilities
- + Comprehensive feature set across modules
- + Scalable for growing practices
Cons
- - Can have a steeper learning curve
- - Pricing can add up with necessary modules/features
- - Interface can feel complex
Verdict
"A powerful, highly customizable solution suitable for practices needing detailed reporting and workflow control, though potentially complex to implement."

Kareo Clinical and Billing
By Tebra (formerly Kareo)
An integrated EHR and practice management solution focused on the needs of independent practices, offering user-friendly interfaces.
Platforms & Use Cases
Platforms: Cloud-based, Mobile App (iOS/Android)
Best For: Small Practices, Independent Physicians, Specialty Clinics, Billing Companies
Key Features
- ✓Intuitive Scheduling: Easy-to-use calendar with color-coding, multi-resource views, and automated reminders.
- ✓Insurance Eligibility Checks: Real-time verification of patient insurance coverage.
- ✓Billing Module: Streamlined charge capture, claims submission, and payment posting.
- ✓Patient Portal & Engagement: Tools for secure messaging, appointment requests, and online payments.
Scorecard (Overall: 8.0 / 10.0)
Pricing
PM Only
$160.00 / Per Provider/Month
- Scheduling
- Basic Billing
- Reporting
Limitations: EHR features separate
Clinical (EHR + PM)
$300.00 / Per Provider/Month
- Full PM
- EHR
- ePrescribing
- Labs
Limitations: Advanced RCM services may cost extra
Pros
- + User-friendly interface
- + Strong focus on independent practices
- + Good mobile accessibility
- + Relatively transparent pricing
Cons
- - Reporting could be more robust
- - Integration options are more limited than some larger competitors
- - Support response times can vary
Verdict
"Excellent choice for small to medium-sized independent practices seeking an easy-to-use, integrated PM and EHR solution."
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athenaOne
By athenahealth
A cloud-based suite combining EHR, practice management, and patient engagement tools, known for its network insights and billing services.
Platforms & Use Cases
Platforms: Cloud-based, Mobile App (iOS/Android)
Best For: Small to Large Practices, Hospitals, Health Systems, Billing Services
Key Features
- ✓Coordinated Scheduling: Manages appointments across multiple providers and locations, with automated reminders.
- ✓Revenue Cycle Management: Robust RCM services with high first-pass claim rates and denial management.
- ✓Patient Portal: Secure portal for appointments, bill pay, messaging, and accessing health information.
- ✓Network Knowledge Base: Leverages data from across its network to inform billing rules and clinical decisions.
Scorecard (Overall: 8.4 / 10.0)
Pricing
Percentage of Collections
Contact Vendor
- Full Suite Access
- RCM Services
- Support
Limitations: Pricing based on % of collections, can be costly for high-revenue practices
Pros
- + Excellent RCM services
- + Strong network insights improve billing
- + Comprehensive feature set
- + Good patient engagement tools
Cons
- - Can be expensive
- - User interface perceived as less modern by some
- - Less customization flexibility
Verdict
"Best for practices prioritizing RCM excellence and willing to pay a percentage of collections for a deeply integrated, network-powered system."

Final Thoughts
The medical practice management software market offers diverse solutions, from comprehensive enterprise platforms like athenaOne and NextGen to user-friendly options for independent practices like Kareo (Tebra) and RXNT. Key differentiators include the depth of RCM services, usability, mobile capabilities, reporting strength, and pricing models. Evaluating specific practice needs against vendor strengths is crucial for selection.